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Fumitremorgin C
英文名：Fumitremorgin C
Cas号：118974-02-0
Cas号：118974-02-0
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 13081129741-0.25mg | 98% | 0 | ￥2160.4 | 请登录 |
| 别 名 | Tryptoquivaline FTC |
| Cas号 | 118974-02-0 |
| M D L | MFCD08702652 |
| 分子式 | C22H25N3O3 |
| 分子量 | 379.45 |
| 产品参数 | |
| 性状 | Fumitremorgin C is a specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter. At 5 μM, it significantly potentiates the toxicity of the chemotherapeutic drugs mitoxantrone, doxorubicin, and topotecan in S1-M1-3.2 colon carcinoma cells. Fumitremorgin C reverses multidrug resistance in cells overexpressing BCRP but not P-glycoprotein (ABCB1) or MRP1 (ABCC1).
Fumitremorgin C is a specific inhibitor of breast cancer resistance protein (BCRP/ABCG2) multidrug efflux transporter. At 5 μM, it significantly potentiates the toxicity of the chemotherapeutic drugs mitoxantrone, doxorubicin, and topotecan in S1-M1-3.2 colon carcinoma cells. Fumitremorgin C reverses multidrug resistance in cells overexpressing BCRP but not P-glycoprotein (ABCB1) or MRP1 (ABCC1). |
| 贮存 | 储存温度:−20°C |
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