本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用。
Atg7 (ATG7)
英文名:Rabbit Monoclonal Antibody
Cas号:
Cas号:
检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113346-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | ATG7 antibody, APG7-LIKE antibody, APG7L antibody, DKFZp434N0735 antibody, GSA7 antibody, Ubiquitin-like modifier-activating enzyme ATG7 antibody, Ubiquitin-activating enzyme E1-like protein antibody |
Cas号 | |
M D L | |
分子式 | |
分子量 | |
产品参数 | 【产品介绍】Autophagy is a process of bulk degradation
of cytoplasmic components by the lysosome/vacuole and has a significant relationship to several neurodegenerative disorders and myopathies in mammals (1). Atg7 (Apg7) is a unique E1 enzyme that is essential for both the Apg12p- and Apg8p-modification systems, and it plays indispensable roles in autophagy (2). A new molecular pathway has been defined, in which activation of the receptor-interacting protein (a serine-threonine kinase) and Jun amino-terminal kinase induced cell death with the morphology of autophagy. Autophagic death required Atg7 and beclin 1 and was induced by caspase-8 inhibition (3). Recommended Applications WB, ICC Applications and Recommended Dilution Factors WB: 1:10,000 - 50,000 ICC: 1:100 - 250 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) 293T, (B) HepG2, and (C) Jurkat cell lysates using anti-Atg7 RabMAb (cat. #5146-1). Immunofluorescent staining of HeLa cells using anti-Atg7 RabMAb (cat.# 5146-1). Specificity A synthetic peptide corresponding to residues in human Atg7 was used as an immunogen. |
性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6251 【用途】WB , ICC 【抗原分子量】72kDa |
贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |