本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床诊断或者治疗，非药用，非食用。
GNB2
英文名：Rabbit Monoclonal Antibody
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113635-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | GNB2 antibody, - antibody, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 antibody, G protein subunit beta-2 antibody, Transducin beta chain 2 antibody |
| Cas号 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 产品参数 | 【产品介绍】Guanine nucleotide binding protein beta-2
(GNB2) is a G-protein subunit belonging to WD repeat G protein beta family. GNB2 functions as a modulator or transducer for trans-membrane signaling pathway systems. G-protein is composed of alpha, beta, and gamma subunits, where beta and gamma subunits are required for GTPase activity and G-protein effector interaction (1). Specifically, GNB2 interacts with the glucocorticoid and migrates into the nucleus to suppress GR-induced trans-activation of the glucocorticoid-responsive genes (2). GNB2 has been identified as a binding partner to Ataxin 10, an important target in SCA10 disorder, and also a partner in regulating NTE, a protein known to cause delayed neuropathy with degeneration of nerve axon (3, 4). Recommended Applications WB, ICC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 ICC: 1:100 - 250 Species Reactivity * Human, Mouse, Rat *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on A) SH-SY5Y, B) Jurkat, and C) NIH3T3 lysates using anti-GNB2 RabMAb (cat. #2515-1). Specificity A peptide corresponding to residues near N-term of human GNB2 was used as an immunogen. |
| 性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR3261Y 【用途】WB , ICC 【抗原分子量】35kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
沪公网安备 31012002003054号