IL-22 (IL22)

英文名:IL-22 (IL22)
Cas号:
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别 名 IL22 antibody, IL-21 antibody, IL-22 antibody, IL-D110 antibody, IL-TIF antibody, IL21 antibody, ILTIF antibody, MGC79382 antibody, MGC79384 antibody, TIFIL-23 antibody, TIFa antibody, zcyto18 antibody, Interleukin-22 antibody, Cytokine Zcyto18 antibody,
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Interleukin-22 (IL-22), an IL-10
family cytokine, is expressed in activated T cells,
Th1 cells and NK cells (1, 2). IL-22 induces expression
of various antimicrobial peptides such as β-defensins
in skin, respiratory, and digestive tissues, which
express IL-22R (1). It also mediates the crosstalk
between leukocytes and tissue epithelia because its
receptor is preferentially expressed on various
tissue epithelial cells. IL-22 is essential for host
defense against infections of extracellular pathogens,
such as bacteria and yeasts, by eliciting various
innate defensive mechanisms from tissue epithelial cells
and promoting wound-healing responses (2). Enhanced
IL-22 levels have been linked to various states
of immunoactivation as seen in the context of
infection, autoimmunity, and allergic disorders (3).

Recommended Applications
WB
Applications and Recommended Dilution Factors
WB: 1:50,000 - 200,000
Species Reactivity *
Human
*Species cross-reactivity is based on WB analysis.
Products Data

Western blot analysis on 10 ng of full-length
IL-22 recombinant protein using anti-IL-22 RabMAb
(cat. #5229-1).

Specificity
A synthetic peptide corresponding to residues in human
IL-22 was used as an immunogen.
性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human
【克隆 ID】EPR5741
【用途】WB
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】14kDa
贮存 Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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