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Recombinant Human Interleukin-16, 130a.a.
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| 性状 | Recombinant Human Interleukin-16, 130a.a. 是一种来源于 E. coli 的含有 130 个氨基酸的促炎细胞因子。
Synonyms rHuIL-16; Lymphocyte chemoattractant factor; LCF Species Human Source E. coli Accession Q14005 Gene ID 3603 Molecular Weight Approximately 13,400 Da AA Sequence MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 20 mM acetic buffer, pH 5.0, 150 mM NaCl and 0.5 mM DTT. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Interleukin-16, 130a.a. (rHuIL-16, 130a.a.) to 100 µg/mL using ddH2O. Storage & Stability Lyophilized recombinant Human Interleukin-16, 130a.a. (rHuIL-16, 130a.a.) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Recombinant Human IL-16 produced in E. coli is a single, non-glycosylated polypeptide chain containing 130 amino acids. Interleukin-16, a proinflammatory cytokine produced in CD8+ lymphocytes, is synthesized as a precursor protein (pro-IL-16). It is postulated that the C-terminal region of pro-IL-16 is cleaved, releasing bioactive IL-16. IL-16 is produced and secreted predominantly by CD8+ T lymphocytes, and it exerts chemoattractant, growth factor, and other activities on lymphocytes, monocytes, and eosinophils by interaction with CD4[1]. |
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