本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床诊断或者治疗，非药用，非食用。
Recombinant Human BCA-1/CXCL13
| 别 名 | |
| Cas号 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 产品参数 | |
| 性状 | Recombinant Human BCA-1/CXCL13 是一种有效的、选择性B淋巴细胞引诱剂，也是一种B细胞定位趋化因子。
Synonyms rHuBCA-1/CXCL13; C-X-C motif chemokine 13; BCA1; BLC; SCYB13 ; 重组人源 CXC 趋化因子13 (CXCL13) Species Human Source E. coli Accession O43927 Gene ID 10563 Molecular Weight Approximately 10.3 kDa AA Sequence VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP Biological Activity Full biological activity determined by a chemotaxis bioassay using human B cells is in a concentration range of 1.0-10 ng/mL. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 20 mM PB, pH 7.4, 100 mM NaCl. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human BCA-1/CXCL13 (rHuBCA-1/CXCL13) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability Lyophilized recombinant Human BCA-1/CXCL13 (rHuBCA-1/CXCL13) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Human BCA-1/CXCL13 is identified as an efficacious and selective attractant for B lymphocytes, also acts as a B cell homing chemokine. Human BCA-1 competes with radiolabeled interferon gamma (IFN-γ) inducible protein 10 (IP-10) for binding to the human CXCR3 receptor. Furthermore, human BCA-1 is an efficacious attractant for human CXCR3 transfected cells; BCA-1-induced chemotaxis is inhibited by a monoclonal antibody against human CXCR3. Indeed, BCA-1 attenuates the calcium flux induced by IP-10. In addition, human BCA-1 is an agonist in stimulating GTPγS binding[1] |
| 贮存 |
沪公网安备 31012002003054号