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Recombinant Human VEGF-C (HEK293-expressed)

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132823-10 μg 0 ￥3800
- +
1308132823-50 μg 0 ￥10800
- +
偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。
别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human VEGF-C (HEK293-expressed) 在淋巴管的生成过程中发挥作用，主要通过其受体VEGFR-3作用于淋巴管内皮细胞，促进其生存、生长和迁移。
Synonyms
rHuVEGF-C; Vascular endothelial growth factor C; Flt4-L; VRP ; 重组人源血管内皮生长因子C (HEK293细胞表达)
Species
Human

Source
HEK 293

Accession
P49767

Gene ID
7424

Molecular Weight
16-19 kDa

AA Sequence
MAHYNTEILK SIDNEWRKTQ CMPREVCIDV GKEFGVATNT FFKPPCVSVY RCGGCCNSEG LQCMNTSTSY LSKTLFEITV PLSQGPKPVT ISFANHTSCR CMSKLDVYRQ VHSIIRR

Biological Activity
The ED50 is <0.5 μg/mL as measured by HMVEC human microvascular endothelial cells.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human VEGF-C (HEK293-expressed) (rHuVEGF-C) to 100 μg/mL using ddH2O or PBS.

Storage & Stability
Lyophilized recombinant Human VEGF-C (HEK293-expressed) (rHuVEGF-C) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
The main function of VEGF-C is in lymphangiogenesis, where it acts on lymphatic endothelial cells (LECs) primarily via its receptor VEGFR-3 promoting survival, growth and migration[1]. However, in addition to its effect on lymphatic vessels, it can also promote the growth of blood vessels and regulate their permeability. The effect on blood vessels can be mediated via its primary receptor VEGFR-3 or its secondary receptor VEGFR-2[2]. Apart from vascular targets, VEGF-C is also important for neural development and blood pressure regulation[3][4].
贮存
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