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Recombinant Human PD-L1, Fc Chimera (CHO-expressed)
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货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308132913-50 μg | 0 | ¥4200 | 请登录 |
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性状 | Recombinant Human PD-L1, Fc Chimera (CHO-expressed) 在妊娠、组织移植、自身免疫性疾病和肝炎等疾病状态下,对免疫系统的适应性起着重要的抑制作用。
Synonyms rHuPD-L1, Fc Chimera; Programmed death ligand 1; CD274; B7-H1 ; 重组人 PD-L1, Fc 嵌合体 (CHO 表达) Species Human Source CHO Accession Q9NZQ7 Gene ID 29126 Molecular Weight 70-72 kDa AA Sequence FTVTVPKDLY VVEYGSNMTI ECKFPVEKQL DLAALIVYWE MEDKNIIQFV HGEEDLKVQH SSYRQRARLL KDQLSLGNAA LQITDVKLQD AGVYRCMISY GGADYKRITV KVNAPYNKIN QRILVVDPVT SEHELTCQAE GYPKAEVIWT SSDHQVLSGK TTTTNSKREE KLFNVTSTLR INTTTNEIFY CTFRRLDPEE NHTAELVIPE LPLAHPPNER T Biological Activity 1 µg/mL (100 µL/well) of immoblized recombinant human PD-L1/B7-H1-Fc can bind human Biotin-PD-1-Fc with a linear range of 0.1-1 μg/mL. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human PD-L1, Fc Chimera (CHO-expressed) (rHuPD-L1, Fc Chimera) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human PD-L1, Fc Chimera (CHO-expressed) (rHuPD-L1, Fc Chimera) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Programmed death-ligand 1 (PD-L1) has been speculated to play a major role in suppressing the adaptive arm of immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. Normally the adaptive immune system reacts to antigens that are associated with immune system activation by exogenous or endogenous danger signals[1] |
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