本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床诊断或者治疗，非药用，非食用。
Recombinant Human RANK L/TNFSF11
英文名：
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308132941-10 μg | 0 | ￥6400 | 请登录 |
| 别 名 | |
| Cas号 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 产品参数 | |
| 性状 | Recombinant Human RANK L/TNFSF11 是来源于 E. coli 的 TNF 相关的活化诱导细胞因子。Recombinant Human RANK L/TNFSF11 诱导 JNK 的激活，增强 T 细胞生长和树突细胞功能，诱导破骨细胞生成和淋巴结器官生成。
Synonyms rHuRANK L/TNFSF11; TRANCE; CD254 Species Human Source E. coli Accession O14788 Gene ID 8600 Molecular Weight Approximately 22.4 kDa AA Sequence IRAEKAMVDG SWLDLAKRSK LEAQPFAHLT INATDIPSGS HKVSLSSWYH DRGWAKISNM TFSNGKLIVN QDGFYYLYAN ICFRHHETSG DLATEYLQLM VYVTKTSIKI PSSHTLMKGG STKYWSGNSE FHFYSINVGG FFKLRSGEEI SIEVSNPSLL DPDQDATYFG AFKVRDID Biological Activity The ED50 is 0.15 μg/mL as measured. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 20 mM Tris and 150 mM NaCl, pH 8.0. Endotoxin Level <1.0 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human RANK L/TNFSF11 (rHuRANK L/TNFSF11) to 100 µg/mL using ddH2O. Storage & Stability Lyophilized recombinant Human RANK L/TNFSF11 (rHuRANK L/TNFSF11) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Receptor activator of NF-κB ligand (RANKL), its cellular receptor, receptor activator of NF-κB (RANK), and the decoy receptor osteoprotegerin (OPG) constitute a novel cytokine system. RANKL produced by osteoblastic lineage cells and activated T lymphocytes is the essential factor for osteoclast formation, fusion, activation, and survival, thus resulting in bone resorption and bone loss. RANKL activates its specific receptor, RANK located on osteoclasts and dendritic cells, and its signaling cascade involves stimulation of the c-jun, NF-κB, and serine/threonine kinase PKB/Akt pathways[1]. |
| 贮存 |
- Recombinant Human Vaspin
- Recombinant Human VEGF-121
- Recombinant Mouse VEGF164 (P.pastoris-expressed)
- Recombinant Human Thioredoxin/TXN, His
- Recombinant Human RANK L/TNFSF11
- Recombinant Mouse RANK L/TNFSF11
- Recombinant Mouse RANK L/TNFSF11, His (CHO-expressed)
- Recombinant Human Transforming growth factor-beta receptor type 2, C-Fc (HEK293-expressed)
- Recombinant Mouse Transforming growth factor-beta receptor type 2, C-Fc (HEK293-expressed)
沪公网安备 31012002003054号