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Recombinant Human Aldehyde Dehydrogenase 1-A3, His

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human Aldehyde Dehydrogenase 1-A3, His 是在 N 端带有 His 标签的人重组 ALDH1A3，在大肠杆菌中产生，并表达编码 Met1-Pro512 的靶基因
Synonyms
rHuAldehyde Dehydrogenase 1-A3, His; ALDH-1A3; Aldehyde Dehydrogenase 1-A3 ; 重组人醛脱氢酶 1-A3，His
Species
Human

Source
E. coli

Accession
P47895

Gene ID
220

Molecular Weight
55-60 kDa

AA Sequence
HHHHHHMATA NGAVENGQPD RKPPALPRPI RNLEVKFTKI FINNEWHESK SGKKFATCNP STREQICEVE EGDKPDVDKA VEAAQVAFQR GSPWRRLDAL SRGRLLHQLA DLVERDRATL AALETMDTGK PFLHAFFIDL EGCIRTLRYF AGWADKIQGK TIPTDDNVVC FTRHEPIGVC GAITPWNFPL LMLVWKLAPA LCCGNTMVLK PAEQTPLTAL YLGSLIKEAG FPPGVVNIVP GFGPTVGAAI SSHPQINKIA FTGSTEVGKL VKEAASRSNL KRVTLELGGK NPCIVCADAD LDLAVECAHQ GVFFNQGQCC TAASRVFVEE QVYSEFVRRS VEYAKKRPVG DPFDVKTEQG PQIDQKQFDK ILELIESGKK EGAKLECGGS AMEDKGLFIK PTVFSEVTDN MRIAKEEIFG PVQPILKFKS IEEVIKRANS TDYGLTAAVF TKNLDKALKL ASALESGTVW INCYNALYAQ APFGGFKMSG NGRELGEYAL AEYTEVKTVT IKLGDKNP

Biological Activity
Data is not available.

Appearance
Solution

Formulation
Supplied as a 0.2 μm filter solution of 20 mM Tris-HCl, 150 mM NaCl, 20% Glycerol, pH 7.5.

Endotoxin Level
<1 EU/μg, determined by LAL method.

Reconstitution
N/A

Storage & Stability
Recombinant Human Aldehyde Dehydrogenase 1-A3, His (rHuAldehyde Dehydrogenase 1-A3, His) is stored at -20°C. It is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Shipping with dry ice.

Background
Aldehyde Dehydrogenase 1-A3 (ALDH1A3) catalyzes the oxidation of retinal to the pleiotropic factor retinoic acid using NAD+. ALDH1A3 participates in various physiological processes in human cells by oxidizing all-trans-retinal to retinoic acid. ALDH1A3 influences a diverse range of biological characteristics within cancer stem cells and can act as a marker for these cells. ALDH1A3 is differentially activated during early embryonic head and forebrain development. ALDH1A3 is considered a target in breast cancer. High expression of ALDH1A3 has been observed in high-grade gliomas (HGGs)[1][2].
贮存
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