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Recombinant Mouse Alpha-1-antitrypsin 1-1, His (HEK293-expressed)
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性状 | Recombinant Mouse Alpha-1-antitrypsin 1-1, His (HEK293-expressed) 是在 C 末端带有 His 标签的小鼠重组 Serpin A1a,由哺乳动物表达系统产生,并表达编码 Glu25-Lys413 的靶基因。
Synonyms rMuAlpha-1-antitrypsin 1-1, His; Serpin A1a; Alpha-1-antitrypsin 1-1 ; 重组小鼠 Alpha-1-抗胰蛋白酶 1-1,His (HEK293 细胞表达) Species Mouse Source HEK 293 Accession P07758 Gene ID 20700 Molecular Weight Approximately 52.0 kDa AA Sequence EDVQETDTSQ KDQSPASHEI ATNLGDFAIS LYRELVHQSN TSNIFFSPVS IATAFAMLSL GSKGDTHTQI LEGLQFNLTQ TSEADIHKSF QHLLQTLNRP DSELQLSTGN GLFVNNDLKL VEKFLEEAKN HYQAEVFSVN FAESEEAKKV INDFVEKGTQ GKIAEAVKKL DQDTVFALAN YILFKGKWKK PFDPENTEEA EFHVDESTTV KVPMMTLSGM LHVHHCSTLS SWVLLMDYAG NATAVFLLPD DGKMQHLEQT LSKELISKFL LNRRRRLAQI HFPRLSISGE YNLKTLMSPL GITRIFNNGA DLSGITEENA PLKLSQAVHK AVLTIDETGT EAAAVTVLQM VPMSMPPILR FDHPFLFIIF EEHTQSPIFL GKVVDPTHKH HHHHH Biological Activity Data is not available. Appearance Solution Formulation Supplied as a 0.2 μm filter solution of 20 mM Tris, 150 mM NaCl, pH 8.0. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution N/A Storage & Stability Recombinant Mouse Alpha-1-antitrypsin 1-1, His (HEK293-expressed) (rMuAlpha-1-antitrypsin 1-1, His) is stored at -20°C. It is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Shipping with dry ice. Background Alpha-1-antitrypsin 1-1 (Serpin A1a; AAT) is the most abundant circulating serine protease inhibitor (serpin) and the prototypic member of the serpin super family. The 52-kD Serpin A1a protein is coded by the gene SERPINA1. Serpin A1a plays an important role in modulating immunity, inflammation, proteostasis, apoptosis, and possibly cellular senescence programs. Systemic deficiency in Serpin A1a due to genetic mutations can result in liver failure and chronic lung disease such as emphysema[1]. |
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