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Recombinant Mouse Angiopoietin-like Protein 3, His (HEK293-expressed)
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| 性状 | Recombinant Mouse Angiopoietin-like Protein 3, His (HEK293-expressed) 是在 C 末端带有 10-His 标签的小鼠重组 ANGPTL3，由哺乳动物表达系统产生，并表达编码 Ser17-Thr455 的靶基因。
Synonyms rMuAngiopoietin-like Protein 3, His; ANGPTL3; Angiopoietin-like Protein 3 ; 重组小鼠血管生成素样蛋白 3，His (HEK293 细胞表达) Species Mouse Source HEK 293 Accession Q9R182 Gene ID 30924 Molecular Weight 25-30 kDa AA Sequence SRVDPDLSSF DSAPSEPKSR FAMLDDVKIL ANGLLQLGHG LKDFVHKTKG QINDIFQKLN IFDQSFYDLS LRTNEIKEEE KELRRTTSTL QVKNEEVKNM SVELNSKLES LLEEKTALQH KVRALEEQLT NLILSPAGAQ EHPEVTSLKS FVEQQDNSIR ELLQSVEEQY KQLSQQHMQI KEIEKQLRKT HHHHHH Biological Activity Data is not available. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS, pH 7.4. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Mouse Angiopoietin-like Protein 3, His (HEK293-expressed) (rMuAngiopoietin-like Protein 3, His) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Mouse Angiopoietin-like Protein 3, His (HEK293-expressed) (rMuAngiopoietin-like Protein 3, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Angiopoietin-like Protein 3 (ANGPTL3) is a 70 kDa 460-amino acid long secretory glycoprotein primarily expressed in the liver. Mature mouse ANGPTL3 contains an N-terminal coiled-coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is implicated in angiogenesis and atherogenesis. ANGPTL3 can regulate serum lipid levels by acting on lipoprotein lipase- (LPL-) and endothelial lipase- (EL-) mediated triglyceride (TG) and phospholipid hydrolysis. Serum ANGPTL3 levels could serve as a biomarker for future occurrence of major adverse cardiovascular events (MACEs) with coronary artery disease (CAD). ANGPTL3 acts as proangiogenic and could induce angiogenesis in vivo via binding of the C-terminal fibrinogen-like domain to the integrin αvβ3 receptor on vascular endothelial cells[1]. |
| 贮存 |
- Recombinant Human Alpha-amylase 2B, His (HEK293-expressed)
- Recombinant Human Amyloid Precursor, C-Fc (HEK293-expressed)
- Recombinant Human Amyloid-like Protein 1, His (HEK293-expressed)
- Recombinant Human Angiogenin
- Recombinant Mouse Angiopoietin-like Protein 3, His (HEK293-expressed)
- Recombinant Human Angiopoietin-like Protein 3, His (HEK293-expressed)
- Recombinant Human Angiopoietin-like Protein 8, N-Fc (HEK293-expressed)
- Recombinant Human Angiopoietin-Related Protein 4, His (HEK293-expressed)
- Recombinant Mouse Angiopoietin-Related Protein 4, C-Fc (HEK293-expressed)
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