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Recombinant Human Apolipoprotein E, His (HEK293-expressed)

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308133051-10 μg 0 ￥1200 请登录
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1308133051-50 μg 0 ￥2800 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human Apolipoprotein E, His (HEK293-expressed) 在 HEK293 细胞中表达，N 端带有一个 His 标签。Recombinant Human Apolipoprotein E (apoE) 以同工型依赖性方式促进胆固醇释放。
Synonyms
rHuApolipoprotein E, His; ApoE; Apolipoprotein E
Species
Human

Source
HEK 293

Accession
P02649

Gene ID
348

Molecular Weight
Approximately 39.0 kDa

AA Sequence
KVEQAVETEP EPELRQQTEW QSGQRWELAL GRFWDYLRWV QTLSEQVQEE LLSSQVTQEL RALMDETMKE LKAYKSELEE QLTPVAEETR ARLSKELQAA QARLGADMED VCGRLVQYRG EVQAMLGQST EELRVRLASH LRKLRKRLLR DADDLQKRLA VYQAGAREGA ERGLSAIRER LGPLVEQGRV RAATVGSLAG QPLQERAQAW GERLRARMEE MGSRTRDRLD EVKEQVAEVR AKLEEQAQQI RLQAEAFQAR LKSWFEPLVE DMQRQWAGLV EKVQAAVGTS AAPVPSDNHH HHHHH

Biological Activity
Data is not available.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against 20 mM PB, 150 mM NaCl, pH 7.4.

Endotoxin Level
<1 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human Apolipoprotein E, His (HEK293-expressed) (rHuApolipoprotein E, His) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability
Lyophilized recombinant Human Apolipoprotein E, His (HEK293-expressed) (rHuApolipoprotein E, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
ApoE isoform specifically inhibits lipid-particle-mediated cholesterol release from neurons. Although apoE and a lipid particle are lipid acceptors, when apoE and a lipid particle form a complex, apoE on the particle surface inhibits the lipid particle-mediated cholesterol release from cells in an apoE-concentration-dependent manner[2].
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