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5-Methylcytosine antibody
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
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产品参数 | 【产品介绍】5-Methylcytosine is the methylated form of
the DNA base cytosine. In mammalian cells, DNA methylation is an enzymatic modification at the 5-position of cytosine present abundantly within the CpG dinucleotide sequence context. This DNA modification is inheritable and reversible without primary DNA base sequence changes resulting in possible epigenetic modulation of phenotype and gene expression (1). CpG methylation may directly interfere with the binding of certain transcriptional regulators to their cognate DNA sequences or may enable recruitment of methyl-CpG binding proteins that create a repressed chromatin environment (2). The de novo formation and maintenance of 5-methylcytosine is catalyzed by DNA methyltransferase proteins (DNMTs) (1). Recommended Applications MeDIP, ICC, ELISA Applications and Recommended Dilution Factors MeDIP: 1 - 5 ug/mL ICC: 1 ug/mL ELISA: 0.1 ug/ml Species Reactivity Human, Mouse, Rat Specificity KLH-5-Methylcytosine was used as immunization. |
性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EP4694 【用途】ICC , ELISA |
贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |