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Caldesmon Phospho (pT753) (CALD1)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113387-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | CALD1 antibody, CDM antibody, H-CAD antibody, HCAD antibody, L-CAD antibody, LCAD antibody, MGC21352 antibody, NAG22 antibody, Caldesmon antibody, antibody |
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| 产品参数 | 【产品介绍】Caldesmon is a smooth muscle and
nonmuscle regulatory protein that interacts with actin, myosin, tropomyosin, and calmodulin (1,2). Smooth muscle caldesmon is an elongated molecule with a calmodulin, tropomyosin, and actin-binding region at the C-terminus and a myosin-binding domain at the N-terminus (3). Caldesmon stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, caldesmon inhibits the actomyosin ATPase by binding to F-actin. This inhibition is reduced by calcium-calmodulin and is promoted by tropomyosin (4). Phosphorylation of non-muscle caldesmon has been linked to reduction of caldesmon's binding properties to actin, myosin, and calmodulin. Also, caldesmon's inhibition of actomyosin ATPase is reduced with its Phosphorylation (5). Recommended Applications WB, ICC Applications and Recommended Dilution Factors WB: 1:1000 - 5000 ICC: 1:50 - 100 Species Reactivity Human Products Data Western blot analysis on HeLa cell lysates using anti-Phospho-Caldesmon (pT753) RabMAb (cat. # 2394-1), 1:5000 dilution. Cells were either (A) untreated (B) treated with Calyculin A. |
| 性状 | 【反应特异性】Human
【克隆 ID】EPR2211Y 【用途】WB , ICC 【抗原分子量】120-150 (smooth muscle)/70-80 |
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