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CARD11
英文名:Rabbit Monoclonal Antibody
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113395-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | CARD11 antibody, BIMP3 antibody, CARMA1 antibody, MGC133069 antibody, Caspase recruitment domain-containing protein 11 antibody, CARD-containing MAGUK protein 1 antibody |
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产品参数 | 【产品介绍】CARD11 belongs to the
membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. It is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). CARD11 has a domain structure similar to that of CARD14. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, CARD11 activated NF-kappaB and induced the phosphorylation of BCL10 (1). Recommended Applications WB Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) Molt-4, (B) Ramos, (C) Jurkat, and (D) K562 cell lysates using anti-CARD11 RabMAb (cat. #3939-1). Specificity A synthetic peptide corresponding to residues on the C-terminus in human CARD11 was used as an immunogen. |
性状 | 【反应特异性】Human
【克隆 ID】EPR2557 【用途】WB 【抗原分子量】133kDa |
贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |