CARD11

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 CARD11 antibody, BIMP3 antibody, CARMA1 antibody, MGC133069 antibody, Caspase recruitment domain-containing protein 11 antibody, CARD-containing MAGUK protein 1 antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】CARD11 belongs to the
membrane-associated guanylate kinase (MAGUK) family, a
class of proteins that functions as molecular scaffolds
for the assembly of multiprotein complexes at
specialized regions of the plasma membrane. It is also
a member of the CARD protein family, which is defined
by carrying a characteristic caspase-associated
recruitment domain (CARD). CARD11 has a domain
structure similar to that of CARD14. The CARD domains
of both proteins have been shown to specifically
interact with BCL10, a protein known to function as
a positive regulator of cell apoptosis and
NF-kappaB activation. When expressed in cells,
CARD11 activated NF-kappaB and induced the
phosphorylation of BCL10 (1).


Recommended Applications

WB
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
Species Reactivity *

Human

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) Molt-4, (B) Ramos,
(C) Jurkat, and (D) K562 cell lysates using
anti-CARD11 RabMAb (cat. #3939-1).


Specificity

A synthetic peptide corresponding to residues on
the C-terminus in human CARD11 was used as an immunogen.
性状 【反应特异性】Human
【克隆 ID】EPR2557
【用途】WB
【抗原分子量】133kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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