Caspase-9 (p35) (CASP9)

英文名:Rabbit Monoclonal Antibody
Cas号:
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
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别 名 CASP9 antibody, APAF-3 antibody, APAF3 antibody, CASPASE-9c antibody, ICE-LAP6 antibody, MCH6 antibody, Caspase-9 subunit p10 antibody, ICE-like apoptotic protease 6 antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Caspase-9 is a member of the
cysteine-aspartic acid protease (caspase) family.
Sequential activation of caspases plays a central role
in the execution-phase of cell apoptosis. Caspases exist
as inactive proenzymes which undergo proteolytic
processing at conserved aspartic residues to produce
two subunits, large (35 kDa) and small (10 kDa),
that dimerize to form the active enzyme. This protein
is processed by caspase APAF1; this step is thought to
be one of the earliest in the caspase activation cascade (1).


Recommended Applications

WB
Applications and Recommended Dilution Factors

WB: 1:10,000 - 50,000
Species Reactivity *

Human

*Species cross-reactivity is based on WB analysis.


Products Data

Western blot analysis on (A) HeLa cell treated
with Camptothecin and (B) HeLa cell lysate
using anti-Caspase-9 (p35) RabMAb (cat. #5103-1).

Specificity

A synthetic peptide corresponding to residues in
human Caspase-9 (p35) was used as an immunogen.

性状 【反应特异性】Human
【克隆 ID】EPR5476
【用途】WB
【抗原分子量】35kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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