CD14

英文名:Rabbit Monoclonal Antibody
Cas号:
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308113412-100ul 现货 0 ¥0 请登录
- +
偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体,下单前请联系客服。
别 名 CD14 antibody, - antibody, Monocyte differentiation antigen CD14, membrane-bound form antibody, Myeloid cell-specific leucine-rich glycoprotein antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】CD14 is a glycophosphatidylinositol-
anchored protein expressed on the surfaces of monocytes
and polymorphonuclear leukocytes. It acts as a
co-receptor for the detection of
bacterial lipopolysaccharide (LPS) (1). CD14 cooperates
with MD-2 and TLR4 to mediate the innate immune response
to bacterial LPS. It acts via MyD88, TIRAP and
TRAF6, leading to NF-kappa-B activation, cytokine
secretion and the inflammatory response (2). CD14
is expressed strongly on peripheral blood monocytes
and macrophages, and weakly on the surface of
granulocytes (1).


Recommended Applications

IHC, ICC
Applications and Recommended Dilution Factors

IHC: 1:100 - 250
ICC: 1:500 - 1000
Species Reactivity

Human


Products Data

Immunohistochemical analysis of paraffin-embedded
human colonic tissue using anti-CD14 RabMAb (cat.# 3890-1).


Immunohistochemical analysis of paraffin-embedded
human tonsil tissue using anti-CD14 RabMAb (cat.# 3890-1).


Specificity

A synthetic peptide corresponding to residues in
the extracellular domain of human CD14 was used as
an immunogen.

性状 【反应特异性】Human
【克隆 ID】EPR3652
【用途】IHC , ICC
【抗原分子量】53kDa
贮存 Storage Condition and Buffer Store at -20° C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用。
X
QQ