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| 生化科研试剂 >> 抗体产品 >> 一抗 |
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CD205 (LY75)
Rabbit Monoclonal Antibody |
| 别 名： |
LY75 antibody, CD205 antibody, CLEC13B antibody, DEC-205 antibody, GP200-MR6 antibody, LY-75 antibody, Lymphocyte antigen 75 antibody, C-type lectin domain family 13 member B antibody, DEC-205 antibody, gp200-MR6 antibody |
| 货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
| 1227177616 |
CD205 (LY75) |
|
100ul |
询价 |
现货 |
3天 |
| 提示信息：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。 |
| 性 状： |
【反应特异性】Human , Mouse
【克隆 ID】EPR5233
【用途】WB , IHC , ICC , IP
【抗原分子量】205kDa |
| 质量标准： |
【产品介绍】CD205 is a type I C-type lectin-like
molecule that acts as an endocytic receptor to
direct captured antigens from the extracellular space to
a specialized antigen-processing compartment (1, 2).
It functions to deliver antigen to dendritic cells
for presentation on MHC class II and cross-presentation
on MHC class I. Thus, CD205 plays an important role in
CD4 and CD8 T cell tolerance induction to self-antigen
both in the periphery and in the thymus. It is expressed
at high levels on cortical thymic epithelium,
thymic medullary DCs (CD11c+ CD8+), and subsets
of peripheral DCs (CD11c+ CD8+ splenic/lymph node
DCs, dermal/interstitial DCs, and Langerhans cells) (2).
In addition, CD205 causes reduced proliferation
of B-lymphocytes (1).
Recommended Applications
WB, IHC, ICC, IP
Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000
IHC: 1:250 - 500
ICC: 1:100 - 250
IP: 1:10 - 100
Species Reactivity * Human, Mouse *Species cross-reactivity is based on WB analysis
Products Data
Western blot analysis on (A) human thymus, (B) human
lymph node, (C) human tonsil, and (D) mouse thymus
lysates using anti-CD205 RabMAb (cat. #3912-1).
Immunohistochemical analysis of paraffin-embedded
human tonsil tissue using anti-CD205 RabMAb (cat. #3912-1).
Specificity
A synthetic peptide corresponding to residues in
the intracellular domain of human CD205 was used
as an immunogen. |
| 贮 存： |
Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt |
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