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CD209
英文名：Rabbit Monoclonal Antibody
Cas号：
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113417-100ul | 现货 | 0 | ￥0 |
| 别 名 | CD209 antibody, CDSIGN antibody, CLEC4L antibody, DC-SIGN antibody, DC-SIGN1 antibody, MGC129965 antibody, CD209 antigen antibody, C-type lectin domain family 4 member L antibody, Dendritic cell-specific ICAM-3-grabbing non-integrin 1 antibody |
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| M D L | |
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| 产品参数 | 【产品介绍】CD209 is a transmembrane receptor and is
often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, ranging from parasites to viruses with a large impact on public health. CD209 is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability. CD209 is closely related in terms of both sequence and function to a neighboring protein L-SIGN. DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution (1). Recommended Applications WB, IHC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:50 - 100 Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) HACAT, (B) fetal skin, (C) fetal artery, and (D) human small intestine lysates using anti-CD209 RabMAb (cat. #5232-1). Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-CD209 RabMAb (cat.# 5232-1). Specificity A synthetic peptide corresponding to residues in human CD209 was used as an immunogen. |
| 性状 | 【反应特异性】Human
【克隆 ID】EPR5588 【用途】WB , IHC 【抗原分子量】50kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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