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COMT
英文名:Rabbit Monoclonal Antibody
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113458-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | COMT antibody, - antibody, Catechol O-methyltransferase antibody, antibody |
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产品参数 | 【产品介绍】Catechol-O-methyltransferase catalyzes
the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson's disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini (1). Recommended Applications WB, IHC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:50 - 100 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) fetal liver, (B) A431, (C) Molt-4, and (D) 293T cell lysates using anti-COMT RabMAb (cat. #5454-1). Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-COMT RabMAb (cat. #5454-1). Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-COMT RabMAb (cat. #5454-1). Specificity A synthetic peptide corresponding to residues in human COMT was used as an immunogen. |
性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6490 【用途】WB , IHC 【抗原分子量】24-30kDa |
贮存 | Storage Condition and Buffer Store at -20° C. Buffer: PBS (pH 7.2), 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt. |