CPN1

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 CPN1 antibody, CPN antibody, FLJ40792 antibody, SCPN antibody, Carboxypeptidase N catalytic chain antibody, Anaphylatoxin inactivator antibody, Arginine carboxypeptidase antibody, Carboxypeptidase N polypeptide 1 antibody, Carboxypeptidase N small subunit
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Carboxypeptidase N is a plasma
metallo-protease that cleaves basic amino acids from the
C terminal of peptides and proteins. CPN1 is important
in the regulation of peptides like kinins
and anaphylatoxins, and it has also been known as
kininase-1 and anaphylatoxin inactivator. It is a
tetramer comprised of two identical regulatory subunits
and two identical catalytic subunits; CPN1 is the
catalytic subunit. Mutations in this protein can
be associated with angioedema or chronic
urticaria resulting from carboxypeptidase N
deficiency (1).
Note: The 48-kDa form is generated by proteolytic
cleavage at the C-terminus. This subunit is cleaved into
a peptide of 27 kDa (2).


Recommended Applications

WB, ICC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
ICC: 1:100 - 250
Species Reactivity *

Human

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) human plasma, (B) HepG2,
and (C) fetal liver lysates using anti-CPN1 RabMAb
(cat. #5322-1).
Specificity

A synthetic peptide corresponding to residues in human
CPN1 was used as an immunogen.


性状 【反应特异性】Human
【克隆 ID】EPR6229
【用途】WB , ICC
【抗原分子量】55/48/27kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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