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DAP12 (TYROBP)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113498-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | TYROBP antibody, DAP12 antibody, KARAP antibody, PLOSL antibody, TYRO protein tyrosine kinase-binding protein antibody, DNAX-activation protein 12 antibody, Killer-activating receptor-associated protein antibody |
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| 产品参数 | 【产品介绍】DAP12 is a transmembrane signaling
polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. It may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. DAP12 may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this protein have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL (1). Recommended Applications WB, ICC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 ICC: 1:250 - 500 Species Reactivity * Human *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) peripheral blood leukocytes, (B) human placenta, and (C) peripheral blood mononuclear cell lysates using anti-DAP12 RabMAb (cat. #5168-1). Specificity A synthetic peptide corresponding to residues in human DAP12 was used as an immunogen. |
| 性状 | 【反应特异性】Human
【克隆 ID】EPR5173 【用途】WB , ICC 【抗原分子量】12kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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