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DARPP-32 (C-term)
英文名:Rabbit Monoclonal IgG
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113502-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | Dopamine- a n d cAMP-regulated neuronal phosphoprotein, DARPP-32 |
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产品参数 | 【产品介绍】The 32kDa dopamine a n d cyclic
adenosine 3'',5''-monophosphate-regulated phosphoprotein (DARPP-32) can either function as a serine/threonine kinase o r as a serine/ threonine phosphatase depending upon which particular amino acid residue is phosph o r ylated (1). When phosph o r ylated by protein kinase A (PKA) at threonine 34, DARPP-32 becomes a potent inhibit o r of protein phosphatase-1 (2-3). Alternatively, when phosph o r ylated at threonine 75 by cyclin-dependent kinase 5(Cdk5), DARPP-32 is converted into an inhibit o r of PKA (1). DARPP-32 a n d t r u n c a t e d DARPP (t-DARPP) are overexpressed in gastric cancers (4). WB: 1:5,000-20,0000 IHC: 1:250-500 ICC: 1:50-100 IP: 1:50 A. Western blot analysis on human brain lysate using anti-DARP-32 (C-term) RabMAb (cat. # 1711-1), dilution 1:20,000. B. Immunohistochemical analysis of paraffin-embedded human gastric adenocarcinoma using anti-DARPP-32 (C-term) RabMAb (cat. # 1711-1). |
性状 | 【反应特异性】Human , Mouse
【克隆 ID】EP721Y 【用途】WB , IHC , ICC , IP 【抗原分子量】32 kDa |
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