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DNA-PK / PRKDC
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113516-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | PRKDC antibody, DNA-PKcs antibody, DNAPK antibody, DNPK1 antibody, HYRC antibody, HYRC1 antibody, XRCC7 antibody, p350 antibody, DNA-dependent protein kinase catalytic subunit antibody, DNPK1 antibody, p460 antibody |
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| 产品参数 | 【产品介绍】DNA-activated serine/threonine protein
kinase (DNA-PK) is a nuclear protein kinase that is involved in DNA nonhomologous end joining (NHEJ) required for double- strand brake repair and V(D)J recombination. DNA-PK is composed of a large catalytic subunit of ~470 kDa (DNA-PKcs) and a DNA binding heterodimer of approximately 70- and 80-kDa subunits called Ku. (1-2). Autophosphorylation of DNA-PK correlates with loss of protein kinase activity and dissociation of the DNA-PKcs-Ku complex. DNA-PK phosphorylates Hsp90, p53 and c-Jun (3-4). Recommended Applications WB, ICC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 ICC: 1:500 - 1000 Species Reactivity * Human *Species cross-reactivity is based on WB analysis Products Data Western blot analysis on (A) K562, (B) Molt-4, (C) MCF-7, (D) SH-SY5Y, (E) 293T, and (F) PC-3 cell lysates using anti-DNA-PK / PRKDC RabMAb (cat. #3922-1). Specificity A synthetic peptide corresponding to residues in human DNA-PK / PRKDC was used as an immunogen. |
| 性状 | 【反应特异性】Human
【克隆 ID】EPR392 【用途】WB , ICC 【抗原分子量】460kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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