DVL2 antibody

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 Dishevelled 2 Phospho (pT224) (DVL2), - antibody, Segment polarity protein dishevelled homolog DVL-2 antibody, DSH homolog 2 antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Dishevelled 2 is a member of the
dishevelled (dsh) protein family. The vertebrate
dsh proteins have approximately 40% amino acid
sequence similarity with Drosophila dsh. Dishevelled 2 is
a 90-kDa protein that undergoes
posttranslational phosphorylation to form a
95-kDa cytoplasmic protein, which may play a role in
the signal transduction pathway mediated by multiple
Wnt proteins. The mechanisms of dishevelled function in
Wnt signaling are likely to be conserved among metazoans (1).


Recommended Applications

WB, IP
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IP: 1:10 - 100
Species Reactivity *

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on HeLa cell lysate using
anti-Phospho-Dishevelled 2 (pT224) RabMAb
(cat. #5287-1). Cells were either (A) untreated
or (B) treated with Calyculin A.

Specificity

A phospho specific peptide corresponding to
residues surrounding Threonine 224 of human Dishevelled
2 was used as an immunogen. This antibody only
detects Dishevelled 2 phosphorylated at Threonine 224.

This antibody was developed as part of a
collaboration between Epitomics, the National
Cancer Institute's Center for Cancer Research and the lab
of Kyung Lee.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPNCIR146
【用途】WB , IP
【抗原分子量】95kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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