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DUX4
英文名:Rabbit Monoclonal Antibody
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113522-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | DUX4 antibody, DUX10 antibody, Double homeobox protein 4 antibody, Double homeobox protein 10 antibody, Double homeobox protein 4/10 antibody |
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产品参数 | 【产品介绍】The DUX4 antibody, clone E5-5, was
recently described in the publication called "Facioscapulohumeral dystrophy: incomplete suppression of a retrotransposed gene." (Snider L et al. PLoS Genet. 2010 Oct 28;6(10):e1001181). DUX4, also known as double homeobox 4, contains two homeoboxes; the repeat-array and open reading frame (ORF) is conserved in other mammals. There was no evidence for transcription from standard cDNA libraries; however, RT-PCR and in-vitro expression experiments indicate that DUX4 has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1. Mutations in DUX4 cause autosomal dominant facioscapulohumeral muscular dystrophy (FSHD) (1). Recommended Applications WB, FC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 FC: 1:10 - 100 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) human testis, (B) HT-1080, (C) PC-3, and (D) HeLa lysates using anti-DUX4 RabMAb (cat. #5158-1). Flow cytometric analysis of permeabilized HeLa cells using anti-DUX4 RabMAb (red) (cat.# 5158-1) or a rabbit IgG (negative) (green). Specificity Recombinant proteins, a mixture of two different protein fragments, of human DUX4 were used as an immunogen. |
性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】E55 【用途】WB , FC 【抗原分子量】45kDa |
贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |