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E-Cadherin (CDH1)
英文名:Rabbit Monoclonal Antibody
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113529-100ul | 现货 | 0 | ¥0 |
别 名 | CDH1 antibody, Arc-1 antibody, CD324 antibody, CDHE antibody, ECAD antibody, LCAM antibody, UVO antibody, E-Cad/CTF3 antibody, Uvomorulin antibody |
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产品参数 | 【产品介绍】E-Cadherin is a classical cadherin from
the cadherin superfamily. It is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in E-Cadherin protein are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites (1). Recommended Applications WB, ICC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 ICC: 1:100 - 250 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) A431, (B) MCF-7, (C) Caco-2, and (D) HeLa cell lysates using anti-E-Cadherin RabMAb (cat. #5409-1). Specificity A synthetic peptide corresponding to residues in human E-Cadherin was used as an immunogen. |
性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR699 【用途】WB , ICC 【抗原分子量】135kDa |
贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |