E-Cadherin Antibody

英文名:Rabbit Monoclonal IgG
Cas号:
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别 名 E-cadherin, Uvom o r ulin, Cadherin-1, CAM 120/80, CD324 antigen
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】E-Cadherin, a member of the
cadherin superfamily, is implicated as a key player
in different cellular processes including development,
m o r phology, polarity, migration a n d tissue
integrity (1-2). E-cadherin is a glycoprotein with
an extracellular domain that interacts with other
E-cadherin molecules on adjacent cells, thereby
establishing adhesion between epithelial cells.
Established as a tum o r a n d metastasis suppress
o r , E-cadherin expression is frequently down-regulated
o r extinguished in malignancy which strongly c o r
relates with po o r prognosis (3-4). Mutations in
E-cadherin are found in gastric, breast, col o r
ectal, thyroid a n d ovarian cancer (5).


WB: 1: 50,000-200,000
IHC: 1:500
ICC: 1:500
IP: 1:50



A. Western blot analysis on MCF-7 cell lysate using
anti-E-cadherin RabMAb (cat. # 1702-1), dilution 1:200,000.

B. Immunohistochemical analysis of paraffin-embedded
human breast carcinoma using anti-E-cadherin RabMAb
(cat. # 1702-1).

C. Immunohistochemical analysis of paraffin-embedded
human hepatocellular carcinoma using anti-E-cadherin
RabMAb (cat. # 1702-1).

性状 【反应特异性】Human , Mouse
【克隆 ID】EP700Y
【用途】WB , IHC , ICC , IP
【抗原分子量】135/80 kDa
贮存
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