eIF-6 (EIF6)

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 EIF6 antibody, CAB antibody, EIF3A antibody, ITGB4BP antibody, b(2)gcn antibody, eIF-6 antibody, p27(BBP) antibody, p27BBP antibody, Eukaryotic translation initiation factor 6 antibody, B(2)GCN homolog antibody, B4 integrin interactor antibody, CAB antibo
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Hemidesmosomes are structures that link
the basal lamina to the intermediate filament
cytoskeleton. An important functional component
of hemidesmosomes is the integrin beta-4 subunit (ITGB4),
a protein containing two fibronectin type III domains.
eIF-6 binds to the fibronectin type III domains of ITGB4
and may help link ITGB4 to the intermediate
filament cytoskeleton. It is insoluble and found in both
the nucleus and cytoplasm, can function as a
translation initiation factor and prevent the association
of the 40S and 60S ribosomal subunits (1).


Recommended Applications

WB, IHC, FC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IHC: 1:100 - 250
FC: 1:100 - 500
Species Reactivity *

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) HeLa, (B) RAW 264.7,
(C) K562, (D) 293T, and (E) HepG2 cell lysates
using anti-eIF-6 RabMAb (cat. #5361-1).

Immunohistochemical analysis of paraffin-embedded
human colonic adenocarcinoma using anti-eIF-6 RabMAb
(cat. #5361-1).

Specificity

A synthetic peptide corresponding to residues in human
eIF-6 was used as an immunogen.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6512(B)
【用途】WB , IHC , FC
【抗原分子量】27kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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