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| 生化科研试剂 >> 抗体产品 >> 一抗 |
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eIF-3E (EIF3E)
Rabbit Monoclonal Antibody |
| 别 名： |
EIF3E antibody, EIF3-P48 antibody, EIF3S6 antibody, INT6 antibody, eIF3-p46 antibody, Eukaryotic translation initiation factor 3 subunit E antibody, Eukaryotic translation initiation factor 3 subunit 6 antibody, Viral integration site protein INT-6 homolo |
| 货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
| 1227177747 |
eIF-3E (EIF3E) |
|
100ul |
询价 |
现货 |
3天 |
| 提示信息：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。 |
| 性 状： |
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6877
【用途】WB , ICC
【抗原分子量】48kDa |
| 质量标准： |
【产品介绍】eIF-3E is the p48 subunit of the
translational initiation factor eIF3. It forms a
multi-factor complex with eIF1, eIF5, and the
eIF2-GTP-Met-tRNA ternary complex that binds to the
40S ribosomal subunit to form the 43S preinitiation
complex (PIC). eIF-3E also prevents the premature joining
of the 60S ribosomal subunit until the start codon
is recognized. In addition, eIF-3E plays a role
in recruiting eIF4G-associated mRNAs to the 43S PIC to
form the 48S PIC and initiate mRNA scanning (1). It
is required for nonsense-mediated mRNA decay (NMD) and
acts in conjunction with UPF2 to divert mRNAs
from translation to the NMD pathway. eIF-3E also
interacts with MCM7 and EPAS1 and regulate the
proteasome-mediated degradation of these proteins (2).
Recommended Applications
WB, ICC
Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000
ICC: 1:100 - 250
Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) Jurkat, (B) 293T,
(C) BxPC-3, (D) A431, (E) Saos-2, (F) HepG2, and (G)
NIH/3T3 cell lysates using anti-eIF-3E RabMAb (cat. #5387-1). Specificity A synthetic peptide corresponding to residues in
human eIF-3E was used as an immunogen. |
| 贮 存： |
Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt |
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