本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床诊断或者治疗，非药用，非食用。
eIF-3E (EIF3E)
英文名：Rabbit Monoclonal Antibody
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113543-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | EIF3E antibody, EIF3-P48 antibody, EIF3S6 antibody, INT6 antibody, eIF3-p46 antibody, Eukaryotic translation initiation factor 3 subunit E antibody, Eukaryotic translation initiation factor 3 subunit 6 antibody, Viral integration site protein INT-6 homolo |
| Cas号 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 产品参数 | 【产品介绍】eIF-3E is the p48 subunit of the
translational initiation factor eIF3. It forms a multi-factor complex with eIF1, eIF5, and the eIF2-GTP-Met-tRNA ternary complex that binds to the 40S ribosomal subunit to form the 43S preinitiation complex (PIC). eIF-3E also prevents the premature joining of the 60S ribosomal subunit until the start codon is recognized. In addition, eIF-3E plays a role in recruiting eIF4G-associated mRNAs to the 43S PIC to form the 48S PIC and initiate mRNA scanning (1). It is required for nonsense-mediated mRNA decay (NMD) and acts in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. eIF-3E also interacts with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins (2). Recommended Applications WB, ICC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 ICC: 1:100 - 250 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) Jurkat, (B) 293T, (C) BxPC-3, (D) A431, (E) Saos-2, (F) HepG2, and (G) NIH/3T3 cell lysates using anti-eIF-3E RabMAb (cat. #5387-1). Specificity A synthetic peptide corresponding to residues in human eIF-3E was used as an immunogen. |
| 性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6877 【用途】WB , ICC 【抗原分子量】48kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
沪公网安备 31012002003054号