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EPS15R Rabbit Antibody
英文名：Rabbit Monoclonal IgG
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113556-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | Eps15-related protein, Eps15R |
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| M D L | |
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| 产品参数 | 【产品介绍】EPS15 a n d EPS15R are substrates of
the epidermal growth fact o r (EGF) recept o r kinase that are characterized by the presence of a protein: protein interaction domain, the EH domain, a n d by their ability to bind to the clathrin adapt o r protein complex adapt o r protein 2. Evidence suggests that eps15 a n d eps15R are involved in endocytosis (1). The most striking difference between these two related proteins is that Eps15R is also found in the nucleus, whereas Eps15 is excluded from this compartment at steady state (2). Eps15R plays a key role in clathrin-mediated endocytosis of transmembrane recept o r s. Using a mutational approach, it has been found that the second ubiquitin-interacting motif (UIM) of Eps15 a n d Eps15R is essential f o r their ubiquitination (3). WB: 1:50,000 IHC: 1:100 250 ICC: 1:50 100 Flow Cytometry: 1:10 IP: 1:70 A. Western blot analysis on Hela cell lysate using anti-EPS15R RabMAb (cat. # 1857-1), dilution 1:50,000. B. Immunohistochemical staining of paraffin-embedded human breast carcinoma using anti-EPS15R RabMAb (cat. #1857-1). |
| 性状 | 【反应特异性】Human
【克隆 ID】EP1145Y 【用途】WB , IHC , ICC , FC , IP 【抗原分子量】125/108/76 (3 isof o r ms) kDa |
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