Factor IX (F9)

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 F9 antibody, FIX antibody, HEMB antibody, MGC129641 antibody, MGC129642 antibody, P19 antibody, PTC antibody, Coagulation factor IXa heavy chain antibody, Christmas factor antibody, Plasma thromboplastin component antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Factor IX is vitamin K-dependent
coagulation factor IX that circulates in the blood as
an inactive zymogen. This factor is converted to an
active form by factor XIa, which excises the
activation peptide and thus generates a heavy chain and
a light chain held together by one or more disulfide
bonds. The role of this activated factor IX in the
blood coagulation cascade is to activate factor X to
its active form through interactions with Ca+2
ions, membrane phospholipids, and factor VIII.
Alterations of this protein, including point
mutations, insertions and deletions, cause factor
IX deficiency, which is a recessive X-linked disorder,
also called hemophilia B or Christmas disease (1).


Recommended Applications

WB, ICC, FC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
ICC: 1:50 - 100
FC: 1:10 - 100
Species Reactivity *

Human

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) HepG2 and (B) human
plasma lysates using anti-Factor IX RabMAb
(cat. #5332-1).

Flow cytometric analysis of permeabilized HepG2 cells
using anti-Factor IX RabMAb (red) (catalog # 5332-1) or
a rabbit IgG (negative) (green).

Specificity

A synthetic peptide corresponding to residues in
human Factor IX was used as an immunogen.
性状 【反应特异性】Human
【克隆 ID】EPR6187
【用途】WB , ICC , FC
【抗原分子量】59kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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