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Factor XIII A (F13A1)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113571-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | F13A1 antibody, F13A antibody, Coagulation factor XIII A chain antibody, Protein-glutamine gamma-glutamyltransferase A chain antibody, Transglutaminase A chain antibody |
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| 产品参数 | 【产品介绍】Factor XIII (plasma transglutaminase,
fibrin stabilizing factor) is a plasma protein that plays an important role in the final stages of blood coagulation and fibrinolysis. It circulates in blood as a tetramer consisting of two "A" and two "B" subunits (1, 2). The amino acid sequence of the enzymatically active subunit, Factor XIII A, is unique and does not exhibit internal homology, but its active center is similar to that of the thiol proteases. Factor XIII A is activated by thrombin and calcium ion to a transglutaminase that catalyzes the cross linking of fibrin molecules, forming intermolecular isopeptide bonds, thus stabilizing blood clots (3, 4). In two diseases that share some histological resemblance (Lymphocyte-poor graft-versus-host-reaction and toxic epidermal necrolysis), Factor-XIII A-positive dendrocytes show some morphological changes, probably as a response to altered cytokine environment. Factor-XIII A-positive dendrocytes thus are reported to possibly play a role in the regulation of the connective tissue remodeling that may accompany epidermal destruction (5). Recommended Applications WB, IHC, IP Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:100 - 250 IP: 1:20 Species Reactivity * Human *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on PBMC cell lysate using anti-Factor XIII A RabMAb (cat. # 2559-1). B. Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-FactirXIII A RabMAb. Note positive staining of dendrocytes within the papillary dermis (cat. #2559-1). Specificity A synthetic peptide corresponding to residues in human Factor XIII A was used as an immunogen. |
| 性状 | 【反应特异性】Human
【克隆 ID】EP3372 【用途】WB , IHC , IP 【抗原分子量】80kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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