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FGR
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113585-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | FGR antibody, FLJ43153 antibody, MGC75096 antibody, SRC2 antibody, c-fgr antibody, c-src2 antibody, p55-Fgr antibody, p55c-fgr antibody, p58c-fgr antibody, Tyrosine-protein kinase Fgr antibody, Proto-oncogene c-Fgr antibody, p55-Fgr antibody |
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| 产品参数 | 【产品介绍】Fgr (c-fgr) is a member of the Src family
of non-receptor protein-tyrosine kinases (PTK’s), which are involved in the intracellular signal transduction for growth and differentiation of the cells. Fgr consists of divergent N-terminal region which is involved in myristylation and palmitylation, conserved SH2 and SH3 internal domain involved in mediating protein-to- protein interactions with phosphotyrosine-containing and proline-rich motifs, and highly conserved C-terminal region tyrosine kinase catalytic domain. Fgr is commonly expressed in cells with hematopoietic origin (e.g. Myeloid cells, NK cells, B cells). Localized in the plasma membrane ruffles, Fgr functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Overexpression of Fgr is seen as a result of Epstein-Barr Virus (EBV) infection (4). Recommended Applications WB, ICC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 ICC: 1:10 - 100 Species Reactivity * Human *Species cross-reactivity is based on WB analysis Products Data Western blot analysis on Raji cell lysate using anti-Fgr RabMAb (cat. # 2517-1). Specificity A synthetic peptide corresponding to C-terminus of human FGR was used as an immunogen. |
| 性状 | 【反应特异性】Human
【克隆 ID】EPR3171 【用途】WB , ICC 【抗原分子量】56kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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