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Fibrinogen gamma chain (FGG)
英文名：Rabbit Monoclonal Antibody
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| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113587-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | FGG antibody, - antibody, Fibrinogen gamma chain antibody, antibody |
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| 产品参数 | 【产品介绍】Fibrinogen is comprised of two sets of
three polypeptide chains termed alpha, beta and gamma that are joined by disulfide bridging within the N-terminal E domain (1). Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen binds through its gamma chain to cell surface receptors, growth factors, and coagulation factors to perform key roles in fibrin clot formation, platelet aggregation, and wound healing (2). Fibrinogen gamma chain, a fibrinogen gamma-chain variant generated via alternative mRNA processing, binding to thrombin and factor VIII results in clots that are mechanically stiffer and resistant to fibrinolysis (2). Elevated plasma fibrinogen gamma concentration is associated with myocardial infarction (3). Fibrinogen-gamma C-terminal fragments can induce endothelial barrier dysfunction and microvascular leak (4). Recommended Applications WB, IHC Applications and Recommended Dilution Factors WB: 1:500 - 1,000 IHC: 1:100 - 250 Species Reactivity Human Products Data Western blot analysis on human plasma lysates using anti-Fibrinogen gamma chain RabMAb (cat. #2743-1). Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Fibrinogen gamma chain RabMAb (cat. #2743-1). Specificity A synthetic peptide corresponding to residues in human Fibrinogen gamma chain was used as an immunogen. |
| 性状 | 【反应特异性】Human
【克隆 ID】EPR3084 【用途】WB , IHC 【抗原分子量】50kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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