FLCN

英文名:Rabbit Monoclonal Antibody
Cas号:
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货号 规格 货期 库存 价格 会员价 订购
1308113595-100ul 现货 0 ¥0 请登录
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别 名 FLCN antibody, BHD antibody, DKFZp547A118 antibody, FLCL antibody, FLJ45004 antibody, FLJ99377 antibody, MGC17998 antibody, MGC23445 antibody, Folliculin antibody, BHD skin lesion fibrofolliculoma protein antibody, Birt-Hogg-Dube syndrome protein antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Folliculin, or FLCN, functions as a
tumor suppressor. It forms a complex with novel
folliculin-interacting proteins 1 and 2 (FNIP1 and
FNIP2), and 5'-AMP-activated protein kinase (AMPK),
an important energy sensor in cells that
negatively regulates mammalian target of rapamycin
(mTOR) (1). FLCN is associated with Smith-Magenis
syndrome. Mutations in FLCN are associated
with Birt-Hogg-Dube syndrome, which is characterized
by fibrofolliculomas, renal tumors, lung cysts,
and pneumothorax (2).


Recommended Applications

WB
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
Species Reactivity *

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis

Products Data

Western blot analysis on (A) 293T and (B) NCCIT cell
lysates using anti-FLCN RabMAb (cat. #3929-1).

Specificity

A recombinant GST-tagged protein fragment corresponding
to human FLCN was used as an immunogen.

This antibody was developed as part of a
collaboration between Epitomics, the National
Cancer Institute's Center for Cancer Research and the
lab of Marston Linehan.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPNCIR147
【用途】WB
【抗原分子量】70kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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