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Alpha-Actinin 4
英文名：Alpha-Actinin 4
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308114371-100ul | 现货 | 0 | ￥3575 | 请登录 |
| 别 名 | ACTN4, Alpha-actinin-4, Non-muscle alpha-actinin 4, F-actin cross-linking protein |
| Cas号 | |
| M D L | |
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| 产品参数 | 【产品介绍】Alpha-actinin is a ubiquitously
expressed cytoskeletal protein found in numerous actin structures. It consists of an N-terminal actin-binding domain, a central rod domain, and a C-terminal domain; the protein functions as a homodimer to cross-link actin filaments. The rod domain determines the distance between cross-linked actin filaments and also serves as an interaction site for several cytoskeletal and signaling proteins (1). Alpha-actinin 4 is a non-muscle isoform version of alpha-actinin that is concentrated in the cytoplasm (2). It plays a role in cell motility, invasion, and metastasis of cancer cells (3). Alpha-actinin 4 is commonly expressed in filopodia, lamellipodia, stress fibers, and sites of adhesion (4). Recommended Applications WB, IHC, ICC, IP Applications and Recommended Dilution Factors WB IHC ICC FC IP 1:1,000 - 10,000 1:100 - 250 1:100 - 250 1:10 - 100 Species Reactivity* Human Mouse Rat Positive Positive Positive Product Data Western blot analysis on (A) fetal skeletal muscle, (B) A431, (C) MCF-7, and (D) HeLa cell lysates using anti-Alpha-Actinin 4 RabMAb (cat. # 2885-1). Immunohistochemical staining of paraffin-embedded human kidney tissue using anti-Alpha-Actinin 4 RabMAb (cat. #2885-1). Immunofluorescent staining of HeLa cells using anti-Actinin 4 RabMAb (cat. #2885-1). Specificity A synthetic peptide corresponding to residues on the N-terminus in human Alpha-Actinin 4 was used as an immunogen. |
| 性状 | 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat 【克隆 ID】EPR2533(2) 【用途】WB , IHC , ICC , IP 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】100 kDa |
| 贮存 | Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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