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Beta-Tubulin
英文名：Beta-Tubulin
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308114376-100ul | 现货 | 0 | ￥3575 | 请登录 |
| 别 名 | TUBB, TUBB5, Tubulin beta chain, Tubulin beta-5 chain |
| Cas号 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 产品参数 | 【产品介绍】Microtubules are essential parts in
eukaryotic cell structures, transportation, and mitosis and consists mainly of 2 soluble protein subunits, alpha and beta tubulin. Beta-tubulin binds to alpha tubulin to form tubulin heterodimer which is posttranslationally modified (1). The tubulin dimer complex binds to GTP and assembles onto the positive ends of microtubules. After incorporation into the microtubules, bound GTP is hydrolyzed by beta tubulin. The stability of the dimer in the microtubules is depended on presence of beta tubulin, where dimer with GTP bound beta-tubulin is stable to microtubule incorporation (2). Mutation on beta-tubulin has been linked to anti-cancer drug resistance in lung cancers (3). Recommended Applications WB, IHC, ICC, FC Applications and Recommended Dilution Factors WB IHC ICC FC IP 1:1,000 - 10,000 1:250 - 500 1:100 - 250 1:10 - 100 Species Reactivity* Human Mouse Rat Positive Positive Positive Product Data Western blot analysis on (A) MCF-7, (B) Jurkat, (C) Ramos, and (D) HeLa cell lysates using anti-Beta- Tubulin RabMAb (cat. # 3124-1). Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-Beta-Tubulin RabMAb (cat. # 3124-1). Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Beta-Tubulin RabMAb (cat. # 3124-1). Immunofluorescent staining of HeLa cells using anti-Beta-Tubulin RabMAb (cat. # 3124-1). Specificity A synthetic peptide corresponding to residues in human Beta-Tubulin was used as an immunogen. |
| 性状 | 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat 【克隆 ID】EPR1330 【用途】WB , IHC , ICC , FC 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】50 kDa |
| 贮存 | Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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