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GAPDH
英文名:GAPDH
Cas号:
Cas号:
检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308114377-100ul | 现货 | 0 | ¥3575 | 请登录 |
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产品参数 | 【产品介绍】Glyceraldehyde-3-phosphate dehydrogenase
(GAPDH) was considered a classical glycolytic protein involved exclusively in cytosolic energy production. However, recent evidence suggests that it is a multifunctional protein displaying diverse activities distinct from its conventional metabolic role. These new roles f o r GAPDH may be dependent on its subcellular localization, oligomeric state o r on the proliferative state of the cell. Results suggest that human cells contain significant intracellular levels of enzymatically inactive GAPDH which is age- independent. The possibility is considered that the functional diversity of GAPDH may be mediated either by posttranslational alteration o r by subcellular protein:protein a n d / o r protein:nucleic acid interactions (1). GAPDH mRNA levels, protein, a n d enzymatic activity have been shown to increase increase in 3T3 cells after exposure to physiological concentrations of insulin (2). Recommended Applications WB, IHC, ICC, IP Applications and Recommended Dilution Factors WB: 1:1000 IHC: 1:100 ICC: 1:50 IP: 1:40 Species Reactivity * Human, Mouse, Rat * *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on (A) NIH/3T3 or (B) HeLa cell lysate using anti-GAPDH RabMAb (cat. # 2251-1), dilution 1:2000. B. Immunohistochemical analysis of paraffin-embedded human colon adenocarcinoma using anti-GAPDH RabMAb (cat. #2251-1). Specificity A synthetic peptide corresponding to residues in human GAPDH was used as an immunogen. |
性状 | 【产品类型】Rabbit Monoclonal IgG
【反应特异性】Human , Mouse , Rat 【克隆ID 】 EPR1977Y 【用途】 WB,IHC,ICC,IP 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】 35 kDa的 |
贮存 | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |