本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床诊断或者治疗，非药用，非食用。
HLA-B
英文名：HLA-B
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308114402-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | HLA-B antibody, AS antibody, Bw-45 antibody, Bw-48 antibody, Bw-56 antibody, HLA-B-5601 antibody, HLA-B-6701 antibody, HLA-B27 antibody, HLA-B73 antibody, HLAB antibody, MGC111087 antibody, SPDA1 antibody, HLA class I histocompatibility antigen, B-7 alpha |
| Cas号 | |
| M D L | |
| 分子式 | |
| 分子量 | |
| 产品参数 | 【产品介绍】HLA-B belongs to the HLA class I heavy
chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide; exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide; exon 4 encodes the alpha3 domain; exon 5 encodes the transmembrane region; and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class I molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. Recommended Applications WB, IHC, ICC, IP Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:100 - 250 ICC: 1:250 - 500 IP: 1:10 - 100 Species Reactivity Human Products Data Western blot analysis on (A) Ramos, (B) HL-60, (C) Jurkat, and (D) TF-1 cell lysates using anti-HLA-B RabMAb (cat. # 2389-1). Immunohistochemical staining of paraffin-embedded human tonsils using anti-HLA-B RabMAb (cat. #2389-1). Specificity A synthetic peptide corresponding to residues in human HLA-B was used as an immunogen. |
| 性状 | 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human 【克隆 ID】EP2624 【用途】WB , IHC , ICC , IP 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】44kDa |
| 贮存 | Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
沪公网安备 31012002003054号