HLA-C

英文名:HLA-C
Cas号:
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别 名 HLA-C antibody, D6S204 antibody, FLJ27082 antibody, HLA-Cw antibody, HLA-JY3 antibody, HLC-C antibody, PSORS1 antibody, HLA class I histocompatibility antigen, Cw-1 alpha chain antibody, MHC class I antigen Cw*1 antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】HLA-C belongs to the HLA class I heavy
chain paralogues. This class I molecule is a
heterodimer consisting of a heavy chain and a light
chain (beta-2 microglobulin). The heavy chain is anchored
in the membrane. Class I molecules play a central role
in the immune system by presenting peptides derived
from endoplasmic reticulum lumen. They are expressed
in nearly all cells. The heavy chain is approximately
45 kDa. Mutations in HLA-C are responsible for the
peptide binding specificity of each class one
molecule. Typing for these polymorphisms is routinely
done for bone marrow and kidney transplantation (1).

Recommended Applications
WB, IP
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
IP: 1:10 - 100
Species Reactivity *
Human, Mouse, Rat
*Species cross-reactivity is based on WB analysis.
Products Data

Western blot analysis on (A) Jurkat, (B) human melanoma,
(C) human placenta, (D) 293T, and (E) A375 lysates
using anti-HLA-C RabMAb (cat. #5472-1).

Specificity
A synthetic peptide corresponding to residues in human
HLA-C was used as an immunogen.
性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6749
【用途】WB , IP
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】45kDa
贮存 Store at -20° C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
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