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IKK beta
英文名：IKBKB
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308114437-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | IKBKB antibody, FLJ33771 antibody, FLJ36218 antibody, FLJ38368 antibody, FLJ40509 antibody, IKK-beta antibody, IKK2 antibody, IKKB antibody, MGC131801 antibody, NFKBIKB antibody, Inhibitor of nuclear factor kappa-B kinase subunit beta antibody, Nuclear fa |
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| 产品参数 | 【产品介绍】IKK-beta (I-Kappa-B kinase-beta) is a member
of the IKK complex which is composed of IKK-alpha, IKK-beta, IKK-gamma and IKAP (1-2). Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquitination. IKK-beta has been shown to activate NF-kB and phosphorylate IKB-alpha and beta (3). Phosphorylation of 2 sites at the activation loop of IKK-beta is essential for activation of IKK by TNF and IL1. Once activated, IKK-beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response (4). Additionally, IKK-beta activity can also be regulated by MEKK-1 (5). Recommended Applications WB, IHC, ICC Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:100 - 250 ICC: 1:50 - 100 Species Reactivity * Human, Mouse, Rat *Cross reactivity with mouse determined by western blot and IHC. Cross reactivity with rat determined by western blot only. Products Data Western blot analysis on (A) HeLa and (B) 293T cell lysates using anti-IKK beta (IKBKB) RabMAb (cat. #3902-1). Immunohistochemical analysis of paraffin-embedded human cervix carcinoma tissue using anti-IKK beta (IKBKB) RabMAb (cat. #3902-1). Immunofluorescent staining of HeLa cells using anti-IKK beta (IKBKB) RabMAb (cat. #3902-1). Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-IKK beta (IKBKB) RabMAb (cat. #3902-1). Specificity A synthetic peptide corresponding to residues at the N-terminus of human IKK beta was used as an immunogen. |
| 性状 | 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat 【克隆 ID】EPR6043 【用途】WB , IHC , ICC 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】85kDa |
| 贮存 | Store at -20° C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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