IKK epsilon

英文名:IKBKE
Cas号:
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别 名 IKBKE antibody, IKK-E antibody, IKK-i antibody, IKKE antibody, IKKI antibody, KIAA0151 antibody, MGC125294 antibody, MGC125295 antibody, MGC125297 antibody, Inhibitor of nuclear factor kappa-B kinase subunit epsilon antibody, Inducible I kappa-B kinase an
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】IKK epsilon is a noncanonical I-kappa-B
kinase (IKK) that is essential for regulating
antiviral signaling pathways. It has also been identified
as a breast cancer oncogene and is amplified
and overexpressed in over 30% of breast carcinomas
and breast cancer cell lines (1). IKK epsilon
phosphorylates inhibitors of NF-kappa-B thus leading to
the dissociation of the inhibitor/NF-kappa-B complex
and ultimately the degradation of the inhibitor. It plays
a special role in the immune response. IKK epsilon
protects cells against DNA damage-induced cell death (2).

Recommended Applications
WB, IHC, ICC, FC
Applications and Recommended Dilution Factors
WB: 1:10,000 - 50,000
IHC: 1:100 - 250
ICC: 1:100 - 250
FC: 1:10 - 100
Species Reactivity *
Human
*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) HeLa, (B) Raji, (C) MCF-7,
and (D) Jurkat cell lysates using anti-IKK epsilon
RabMAb (cat. #5169-1).

Immunohistochemical analysis of paraffin-embedded
human tonsil tissue using anti-IKK epsilon RabMAb
(cat. #5169-1).

Specificity
A synthetic peptide corresponding to residues in human
IKK epsilon was used as an immunogen.
性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human
【克隆 ID】EPR4904
【用途】WB , IHC , ICC , FC
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】80kDa
贮存 Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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