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Recombinant Human Betacellulin
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| 性状 | Recombinant Human Betacellulin 是一种糖蛋白，能够通过提高来自导管和胰腺腺泡细胞的 β 细胞的分化和再生来提高葡萄糖耐受性。
Synonyms rHuBetacellulin; Probetacellulin; BTC ; 重组人乙胞素因子 Species Human Source E. coli Accession P35070 Gene ID 685 Molecular Weight Approximately 15 kDa AA Sequence MDGNSTRSPE TNGLLCGDPE ENCAATTTQS KRKGHFSRCP KQYKHYCIKG RCRFVVAEQT PSCVCDEGYI GARCERVDLF Y Biological Activity The ED50 is <0.01 ng/mL as measured by murine Balb/3T3 cells, corresponding to a specific activity of >1.0 × 108 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Betacellulin (rHuBetacellulin) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Human Betacellulin (rHuBetacellulin) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Betacellulin (BTC), a member of the epidermal growth factor family, is expressed predominantly in the human pancreas and induces the differentiation of a pancreatic acinar cell line (AR42J) into insulin-secreting cells. Betacellulin binds and activates the EGF receptor (EGFR/erbB-1) and erbB-4, and it induces tyrosine phosphorylation of erbB-2, which couples with the EGFR or erbB-4[1]. |
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- 重组人FGF-ACIDIC
- Recombinant Human Amphiregulin
- Recombinant Human B cell Activating Factor/TNFSF13B
- 重组人FGF-BASIC
- Recombinant Human Betacellulin
- Recombinant Human Bone Morphogenetic Protein 2
- Recombinant Human Bone Morphogenetic Protein 4
- Recombinant Human Bone Morphogenetic Protein 7
- Recombinant Human Endostatin (P.pastoris-expressed)
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