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Recombinant Human Interferon-gamma

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132530-10 μg 0 ￥1200 请登录
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1308132530-50 μg 0 ￥2400 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human Interferon-gamma 是一种细胞因子，具有免疫调节作用，可抗病毒、抗肿瘤等。
Synonyms
rHuIFN-γ; IFNG; IFN-gamma; Interferon gamma ; 重组人干扰素-γ
Species
Human

Source
E. coli

Accession
P01579

Gene ID
3458

Molecular Weight
Approximately 17 kDa

AA Sequence
MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFRGR RASQ

Biological Activity
The ED50 is <0.05 ng/mL as measured by HT‐29 cells.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<1 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human Interferon-gamma (rHuIFN-γ) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability
Lyophilized recombinant Human Interferon-gamma (rHuIFN-γ) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Human Interferon-gamma (hIFNγ) is naturally produced by CD4+ T helper cell type 1 (Th1) lymphocytes, CD8+ cytotoxic lymphocytes, natural killer (NK) cells, B cells, NKT cells, and professional antigen-presenting cells (APCs). Secretion of hIFNγ by NK cells and APCs is important in early host reactions against infection while production of hIFNγ by T lymphocytes is important in the adaptive immune response. hIFNγ shows antiviral and antitumor activity and is involved in complex interactions of cellular metabolism and differentiation[1]. Interferon-gamma (IFN-γ) is a cytokine with potent immunomodulatory propertiy. IFN-γ activates cells via a different receptor than IFN-α and IFN-β, which accounts for the different physiological properties of the proteins[2].
贮存
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