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Recombinant Mouse Interleukin-13, His (CHO-expressed)

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132602-10 μg 0 ￥4800 请登录
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1308132602-50 μg 0 ￥16800 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Mouse Interleukin-13, His (CHO-expressed) 是一种 CHO 细胞来源的重要细胞因子，是一种多功能细胞因子，其主要作用是减少炎症反应。

Synonyms
rMuIL-13, His; P600
Species
Mouse

Source
E. coli

Accession
P20109

Gene ID
16163

Molecular Weight
Approximately 14 kDa

AA Sequence
PVPRSVSLPL TLKELIEELS NITQDQTPLC NGSMVWSVDL AAGGFCVALD SLTNISNCNA IYRTQRILHG LCNRKAPTTV SSLPDTKIEV AHFITKLLSY TKQLFRHGPF HHHHHH

Biological Activity
The ED50 is <20 ng/mL as measured by human TF-1 cells.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Murine Interleukin-13, His (CHO-expressed) (rMuIL-13, His) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability
Lyophilized recombinant Murine Interleukin-13, His (CHO-expressed) (rMuIL-13, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Interleukin (IL)-13 plays a pivotal role in the pathogenesis of allergic asthma. Passive administration of its monoclonal antibody or soluble receptor to block overproduced IL-13 has been proven to be effective in controlling airway allergic responses in animal models, but these approaches have disadvantages of short half-lives, high costs, and possible adverse effects. IL-13 induces the gene expression of Ca2+-activating chloride channel, stimulates the differentiation of epithelial cells, and promotes mucin gene expression and release. IL-13 plays a key role in the pathogenesis of asthma[1].
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