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Recombinant Mouse Platelet-derived Growth Factor-BB

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132613-10 μg 0 ￥3800 请登录
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1308132613-50 μg 0 ￥11800 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Mouse Platelet-derived Growth Factor-BB 是一种有活性的 PDGF 亚型，可用于细胞培养。
Synonyms
rMuPDGF-BB; PDGF-2; GDGF; ODGF; SIS; SSV ; 重组小鼠血小板衍生生长因子-BB
Species
Mouse

Source
E. coli

Accession
P31240

Gene ID
18591

Molecular Weight
Approximately 24.7 kDa

AA Sequence
MSLGSLAAAE PAVIAECKTR TEVFQISRNL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRASQVQMRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETIVTPRPVT

Biological Activity
The ED50 is <2.5 ng/mL as measured by 3T3 cells, corresponding to a specific activity of >4 × 105 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against 10 mM Sodium Citrate, pH 3.0.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Murine Platelet-derived Growth Factor-BB (rMuPDGF-BB) to 100 µg/mL using ddH2O.

Storage & Stability
Lyophilized recombinant Murine Platelet-derived Growth Factor-BB (rMuPDGF-BB) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Platelet-derived growth factor-BB (PDGF-BB) is primarily secreted from platelet α-granules and is the most active PDGF isoform in bone and other connective tissue as it can bind to all known PDGF receptors. PDGF-BB plays an important role in bone regeneration by inducing mitogenesis, chemotaxis, extracellular matrix formation, and vascularization[1].
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