1. 首页
  2. 生化科研试剂
  3. 蛋白质组化

Recombinant Rat Basic Fibroblast Growth Factor

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132616-10 μg 0 ￥2400 请登录
- +
1308132616-50 μg 0 ￥4400 请登录
- +
偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。
别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Rat Basic Fibroblast Growth Factor 是由 FGF2 基因编码的生长因子和信号传导蛋白。
Synonyms
rRtbFGF; HBGF-2; FGF-2; FGF-b; FGF-basic
Species
Rat

Source
E. coli

Accession
P13109

Gene ID
54250

Molecular Weight
Approximately 16.4 kDa

AA Sequence
GPALPEDGGG AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH VKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTE ECFFFERLES NNYNTYRSRK YSSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS

Biological Activity
The ED50 is <0.25 ng/mL as measured by 3T3 cells, corresponding to a specific activity of > 4.0 × 106 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Rat Basic Fibroblast Growth Factor (rRtbFGF) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability
Lyophilized recombinant Rat Basic Fibroblast Growth Factor (rRtbFGF) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Recombinant Rat Basic Fibroblast Growth Factor is a potent mitogen and chemoattractant for endothelial cells as well as fibroblasts. Basic fibroblast growth factor (bFGF) is a heparin-binding mitogen for mesoderm-derived cells, also acts as a mitogen, differentiation inducing and maintenance factor for many neuroectodermal cells including glial cells, neurons, paraneurons, and their tumor counterparts. The molecule is expressed in several types of neuroectodermal cells. bFGF occurs in many neuronal target tissues, and can prevent ontogenetic as well as lesion-induced neuron death[1]. In vitro, basic fibroblast growth factor induces an angiogenic phenotype in endothelial cells, which includes chemotaxis, mitogenesis, protease production, beta-integrin expression, and tube formation in three-dimensional gels. It acts by binding to specific tyrosine kinase receptors and to cell-associated heparan sulfate proteoglycans[2].

贮存
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床诊断或者治疗，非药用，非食用。
X
QQ