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Recombinant Mouse Betacellulin
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308132842-10 μg | 0 | ¥3800 | ||||
1308132842-50 μg | 0 | ¥9800 |
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性状 | Recombinant Mouse Betacellulin 是 E. coli 产生的表皮生长因子家族的一员,可诱导胰腺 β 细胞的分化,促进 β 细胞的再生。
Synonyms rMuBetacellulin; BTC Species Mouse Source E. coli Accession Q05928 Gene ID 12223 Molecular Weight Approximately 9.2 kDa AA Sequence MDGNTTRTPE TNGSLCGAPG ENCTGTTPRQ KVKTHFSRCP KQYKHYCIHG RCRFVVDEQT PSCICEKGYF GARCERVDLF Y Biological Activity The ED50 is <0.5 ng/mL as measured by 3T3 cells, corresponding to a specific activity of >2 × 106 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 50 mM Tris, 300 mM NaCl, pH 9.0. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Mouse Betacellulin (rMuBetacellulin) to 100 µg/mL using ddH2O. Storage & Stability Lyophilized recombinant Mouse Betacellulin (rMuBetacellulin) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, induces differentiation of pancreatic β-cells and promotes regeneration of β-cells in experimental diabetes. BTC stimulates DNA synthesis in fibroblasts and vascular smooth muscle cells. BTC plays a role in regulating growth and/or differentiation of endocrine precursor cells of the fetal pancreas. BTC is found to convert amylase-secreting pancreatic AR42J cells into insulin-producing cells and to have a mitogenic effect in human undifferentiated pancreatic epithelial cells[1]. |
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